Histomonas meleagridis Molecular Traits—From Past to Future

Abstract

The protozoan parasite Histomonas meleagridis is the causative agent of histomonosis, a poultry disease whose significance is underlined by the absence of any licenced prophylaxis or treatment. Considering the parasite-bacteria interplay, histomonosis represents an intriguing interaction inmedicine. The present reviewtargets the molecular research on H. meleagridis, covering the period after re-emergence of histomonosis at the beginning of the twenty-first century until today, from early phylogenetic studies to recent investigations applying omics techniques.