Lesion image generation using conditional gan for metastatic liver cancer detection

Abstract

—In the diagnosis of the abdomen, CT images taken under various conditions are visually checked by multiple doctors. Since diagnosing CT images requires doctors to take time and effort, a Computer-Aided Diagnosis system (CAD) based on a machine learning technique is expected. It is, however, difficult to collect a large number of case images for machine learning. In this paper, we propose a method to generate lesion images by a Conditional Generative Adversarial Networks (CGAN) and show the effectiveness of the proposed method by the accuracy of liver cancer detection from CT images. A CGAN which generates pseudo lesion images is trained with real lesion images labeled with “edge” and “non-edge” of the liver. We confirmed that the proposed method achieved the detection rate of 0.85 and the false positives per case of 0.20. The detection accuracy was higher than that of a conventional method.