Is there a Role for Sterols and Steroids in Fungal Growth and Transition from Yeast to Hyphal-Form and Vice Versa? An Overview

  • Vanden Bossche H
  • Marichal P
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Abstract

Ergosterol seems to be not only the best-suited sterol to maintain fungal membrane integrity and activity; there is evidence that this 24-alkylated sterol is also involved in critical non-membrane associated functions. A number of fungal species contain steroid-binding proteins and vertebrate steroid hormones seem to affect fungal morphogenesis. In this article it is speculated that ergosterol may also playa role in the yeast-to-mycelium transformation. The possible role of steroid hormones and endogenous ligands in fungal growth and morphogenesis is also discussed.

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Vanden Bossche, H., & Marichal, P. (1993). Is there a Role for Sterols and Steroids in Fungal Growth and Transition from Yeast to Hyphal-Form and Vice Versa? An Overview. In Dimorphic Fungi in Biology and Medicine (pp. 177–190). Springer US. https://doi.org/10.1007/978-1-4615-2834-0_15

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