Preparations of Iodotrimethylsilane and Application to Organic Synthesis

Abstract

Iodotrimethylsilane which has a hard acid (Me3Si)- soft base (I) bond displays a strong oxygenophilicity towards ethers, esters, lactones, acetals, and other molecules involving oxygen atom as a functional group. Recent progress of the chemistry of iodotrimethylsilane is reviewed especially from a view point of organic synthesis. The application of bromotrimethylsilane to organic synthesis is also discussed briefly. © 1982, The Society of Synthetic Organic Chemistry, Japan. All rights reserved.