The Great (Nuclear) Escape: New Insights into the Role of the Nuclear Egress Complex of Herpesviruses

  • Bigalke J
  • Heldwein E
24Citations
Citations of this article
39Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Herpesviruses are unusual among enveloped viruses because they bud twice yet acquire a single envelope. They are also the only known viruses that bud into the nuclear envelope. We discovered that the herpesvirus nuclear egress complex could bud membranes without the help of other proteins by forming a coat-like hexagonal scaffold inside the budding membrane. This finding raises the possibility that a phenotypically similar nuclear export of large RNAs is cargo driven.

Cite

CITATION STYLE

APA

Bigalke, J. M., & Heldwein, E. E. (2015). The Great (Nuclear) Escape: New Insights into the Role of the Nuclear Egress Complex of Herpesviruses. Journal of Virology, 89(18), 9150–9153. https://doi.org/10.1128/jvi.02530-14

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free