Cell-penetrating peptides (CPPs) are relatively short peptides that can enter to the cell interior and facilitate intracellular delivery of associated cargo molecules. NickFects is a novel family of CPPs, designed to deliver various types of bio-active cargos using non-covalent nanoparticle formation approach. This chapter describes in details the manual synthesis of cell-penetrating peptides using Fmoc-solid phase peptide synthesis (SPPS).
CITATION STYLE
Arukuusk, P., & Langel, Ü. (2020). Synthesis of nickfects, a new family of CPPs, by solid-phase peptide synthesis. In Methods in Molecular Biology (Vol. 2103, pp. 239–247). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0227-0_16
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