Two cases of vanishing endometrial carcinoma

Abstract

In gynecological cancer, diagnosis is made by biopsy before radical surgery except for ovarian cancers. Endometrial biopsy is a gold standard for endometrial cancer. In some cancers such as prostate and colon as well endometrial cancer final tissue may not confirm presence of cancer although, initial biopsy is positive for malignancy prior to radical surgery. This is called vanishing cancer. In this report, the researchers presented two cases which had been diagnosed endometrioid type endometrial carcinoma on endometrial biopsy sampling. However, in hysterectomy specimen there was no residual cancer. These types of cases exist in low prevalence which may be subjected to medicolegal issue should be known by the clinician, pathologist and patient. © Medwell Journals, 2011.