In its fresh state, the amniochorionic membrane contains various multipotential cells, growth factors, and extracellular matrix proteins that contribute to the healing of chronic vascular ulcers. To demonstrate its effectiveness, a fresh human placental membrane allograft was applied to a chronic venous ulcer in the lower limb of an 89-year-old female patient with a 12 x 10 cm ulcerated lesion of 40 years of evolution in the malleolar area of her left lower limb. Sixty days after the graft, the ulcer was healed in 100% of its surface and a light pink scar on the edges indicated possible pigmentation. Fresh human amniochorionic membrane allograft is a therapeutic alternative for the healing of refractory chronic vascular ulcers of the lower extremities.
CITATION STYLE
Piamo, A., García, M., Romero, D., & Ferrer, D. (2022). Healing of a chronic ulcer of the lower limb of venous origin with fresh human amniochorionic membrane allograft. Biomedica, 42, 17–25. https://doi.org/10.7705/biomedica.6319
Mendeley helps you to discover research relevant for your work.