Abstract
Alterations in DNA methylation occur frequently in virtually all types of cancer. In light of the strong cumulative evidence of the role of epigenetic modifications in carcinogenesis, the epigenome is now considered an attractive candidate for therapeutically targeting cancer. This chapter highlights the role of DNA methylation and its contribution to cancer development and progression, as well as the current and future perspectives of utilising DNA methylation for improving clinical outcomes for cancer patients.
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Patil, V., & Herceg, Z. (2019). DNA Methylation and Carcinogenesis: Current and Future Perspectives. In Clinical Epigenetics (pp. 153–171). Springer Singapore. https://doi.org/10.1007/978-981-13-8958-0_7
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