Synthesis of a symmetric multivalent molecule containing four carbohydrate substituents

Abstract

Starting with allyl- and pent-4-enyl-β-D-glucopyranosides 4-7, different D-Glucose units (8-15) containing alkyl spacers of variable lenght and with different end groups can be prepared. Reaction of four equivalents of the caesium salt derived from propan-4-carboxy-1-yl-2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside 15 with pentaerythrityltetrabromide yields the tetravalent molecule 16. © 1995 Springer-Verlag.