Hydrogen sulfide: A metabolic modulator and a protective agent in animal models of reperfusion injury

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Abstract

Hydrogen sulfide (H2S), a gas with the characteristic odor of rotten eggs, is known for its toxicity and as an environmental hazard [1-5]. Recently H2S has been recognized as a signaling molecule of the cardiovascular, inflammatory and nervous systems. Alongside with nitric oxide (NO) and carbon monoxide, it is now referred to as the third endogenous gaseous transmitter [6]. Inhalation of gaseous H2S and administration of compounds that donate H2S have been studied in various models of ischemia-reperfusion and circulatory shock [7-24]. © 2009 Springer-Verlag New York.

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Szabó, C., Asfar, P., & Radermacher, P. (2007). Hydrogen sulfide: A metabolic modulator and a protective agent in animal models of reperfusion injury. In Yearbook of Intensive Care and Emergency Medicine 2009 (pp. 171–179). Springer New York. https://doi.org/10.1007/978-0-387-92278-2_17

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