Patents Survey: Treatment of Alzheimer's disease through nanotechnology-based drug delivery system

Abstract

Alzheimer's disease (AD) is severe disabling disorder related to cognitive impairment and loss of cholinergic activity. It is a sort of progressive disorder, which has very limited treatment options. The treatment of AD is accompanied by several limitations, including suboptimal concentrations of drug, their gastrointestinal and peripheral cholinergic side effects, and conventional formulation's related issues. Due to multiple problems, conventional therapies are found to be providing improper treatment for AD. Therefore, nanotechnology-based drug delivery was explored with the motive of improving the drug delivery of available AD agents. The extent of advantages of drug delivery through nanotechnology-based systems really provides the superior outcomes as compared to the conventional therapies. This chapter focuses on the patents granted or published for the treatment of AD using different types of nanotechnology-based drug delivery systems. The number of patents granted or published in this area really provides the reason for shifting of paradigm from drug discovery to improvising drug delivery using nanotechnology-based systems.