A review on analytical methods of dapagliflozin: An updat

Abstract

Dapagliflozin is an antidiabetic drug that works on the kidneys of reabsorption of glucose in kidneys by the sodium-glucose co-transporter offer. It is used in patients with type 2 diabetes. It is administered as tablets. It has several analytical papers for estimation of active pharmaceutical ingredient (API) or drug formulation by reverse phase-high performance liquid chromatography (RP-HPLC) and ultraviolet spectroscopy (UV). It is very challenging to use of chemicals, drugs, and solvent of separation methods used in the pharmaceutical product to green chemistry. This review mostly used dihydrogen phosphate buffer and other toxic reagents for estimation and these agents harm instruments, as well as, environment and a lot of waste so that novel analytical techniques for quantifying and defining dapagliflozin should be built as easy as possible and secure for the individual and the community. This review pays attention to the critical condition of physicochemical, properties, action, and aims to focus on different analytical methods for the estimation of dapagliflozin in pharmaceutical formulations.