The impact of MITF on melanoma development: News from bench and bedside

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Abstract

In the current issue, two articles highlight the impact of melanocyte transcription factor (MITF) on melanoma development. In the first, Lister et al. reveal in vivo proof of MITF directly regulating tumor development in BRAF V600E melanomas. In the second, Sturm et al. present a clinical trial that emphasizes the importance of the recently discovered E318K MITF germline mutation in patients with multiple primary melanomas. © 2014 The Society for Investigative Dermatology.

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Roider, E. M., & Fisher, D. E. (2014). The impact of MITF on melanoma development: News from bench and bedside. Journal of Investigative Dermatology. Nature Publishing Group. https://doi.org/10.1038/jid.2013.390

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