Two epimers of siastatin B, 3-episiastatin B (3) and 3, 4-diepisiastatin B (4), were obtained by the chemical modification of siastatin B. Compound 3 showed marked inhibitory activity against influenza virus neuraminidases and significant inhibition of influenza virus infection in vitro. © 1993, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
CITATION STYLE
Nishimura, Y., Umezawa, Y., Kondo, S., Takeuchi, T., Mori, K., Kijima-Suda, I., … Nakamura, K. (1993). Synthesis of 3-episiastatin b analogues having anti-influenza virus activity. Journal of Antibiotics, 46(12), 1883–1889. https://doi.org/10.7164/antibiotics.46.1883
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