Evaluation of the efficacy of miconazole nitrate shampoo for prevention against T. tonsurans infection

Abstract

We report the efficacy of miconazole nitrate shampoo (Furfur Shampoo®) to prevent T. tonsurans infection. Method: Experimental models were made from stratum corneum of healthy human heel or guinea pig skin. Before and/or after T. tonsurans was applied, samples were washed with miconazole nitrate shampoo, then inoculated on a Sabouraud culture plate. Result: Though miconazole nitrate shampoo did not eliminate T. tonsurans on the sample completely, the time required to develop the colony (9.9 days) was obviously extended (7.7 days by control). Discussion: We concluded that miconazole nitrate shampoo is a useful method of preventing T. tonsurans infection, and should be used every day (before/after the chance to infect).