SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

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Abstract

A comparative analysis of 18 rodent species identifies a role for SIRT6-dependent DNA double strand break repair as a major factor in organismal lifespan

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Tian, X., Firsanov, D., Zhang, Z., Cheng, Y., Luo, L., Tombline, G., … Gorbunova, V. (2019). SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell, 177(3), 622-638.e22. https://doi.org/10.1016/j.cell.2019.03.043

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