Genomorama: Genome visualization and analysis

Abstract

Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in these tasks, we present Genomorama, a software program for interactively displaying multiple genomes and identifying potential DNA hybridization sites for assay design. Results: Useful features of Genomorama include genome search by DNA hybridization (probe binding and PCR amplification), efficient multi-scale display and manipulation of multiple genomes, support for many genome file types and the ability to search for and retrieve data from the National Center for Biotechnology Information (NCBI) Entrez server. Conclusion: Genomorama provides an efficient computational platform for visualizing and analyzing multiple genomes. © 2007 Gans and Wolinsky; licensee BioMed Central Ltd.