Abstract
Mice are protected from experimental autoimmune encephalomyelitis (EAE) when fed myelin basic protein (MBP). Thymectomized mice do not exhibit oral tolerance. We found evidence for two mechanisms to explain the role of the thymus in oral tolerance: a site for deletion of autoreactive T cells and a source of regulatory T cells. © 2004 New York Academy of Sciences.
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Song, F., Gienapp, I. E., Shawler, T., Guan, Z., & Whitacre, C. C. (2004). The thymus plays a role in oral tolerance induction in experimental autoimmune encephalomyelitis. In Annals of the New York Academy of Sciences (Vol. 1029, pp. 402–404). New York Academy of Sciences. https://doi.org/10.1196/annals.1309.047
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