Identification of antigenic peptides recognized by cytolytic T lymphocytes (CTL) is a prerequisite for the development of targeted cancer immunotherapy approaches. This chapter provides a global approach for the identification of peptides recognized by CTL. It implies the identification of the HLA molecule presenting the peptide as well as the design and screening of a cDNA library derived from the tumor cells. © Springer Science+Business Media, LLC 2013.
CITATION STYLE
Vigneron, N., Ma, W., Michaux, A., & Van Den Eynde, B. J. (2013). Identifying source proteins for mhc class I-presented peptides. Methods in Molecular Biology, 960, 187–207. https://doi.org/10.1007/978-1-62703-218-6_16
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