Csp3-I bonds, especially those with β-hydrogen atoms, are a class of challenging substrates for the Pd-catalyzed transformations. The challenges mainly stem from the reluctant oxidative addition of C sp3-I bond with Pd(0) species and the facile β-H elimination for alkylpalladium intermediate. Herein, Pd-catalyzed reactions from unactivated Csp3-I bond were discussed. © 2014 IUPAC.
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Liu, H., & Jiang, X. (2014). Pd-catalyzed reactions of unactivated Csp3-I bonds. In Pure and Applied Chemistry (Vol. 86, pp. 307–314). IUPAC Secretariat. https://doi.org/10.1515/pac-2014-5032