Linfoma anaplásico de células T grandes primario cutáneo CD30+. Serie de nueve casos

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Abstract

CD30+ anaplastic large T cell lymphoma is a cutaneous primary lymphoma in which there is no evidence of systemic disease; histopathological study is required for its diagnosis. Objective: To present the cases diagnosed with primary cutaneous CD30+ anaplastic large T-cell lymphoma over a 24-year period in Hospital General “Dr. Manuel Gea González” Department of Dermatology. Method: Retrospective study. Descriptive statistics was carried out. Information was collected on gender, age, clinical characteristics, complementary test results, previous and current treatments, histopathological studies reports and immunohistochemistry test results. Results: Of 29 309 records, nine patients (0.000034%) with a diagnosis of CD30+ anaplastic T cell lymphoma were found. Histopathological and immunohistochemical diagnosis was confirmed by two certified dermatopathologists. Average age was 61.2 years, and there was a predominance of the female gender, with initial clinical presentation as a papular or nodular lesion and varied topography. Conclusions: The prognosis of CD30+ anaplastic large T cell lymphoma in the studied population was dependent on clinical stage. The treatment at early stages has favorable results.

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Ruiz-Arriaga, L. F., Landgrave-Gómez, I., Toussaint-Caire, S., Lacy-Niebla, R. M., & Vega-Memije, M. E. (2019). Linfoma anaplásico de células T grandes primario cutáneo CD30+. Serie de nueve casos. Gaceta Medica de Mexico, 155(2), 130–135. https://doi.org/10.24875/gmm.m19000244

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