Gene regulatory networks in plants: Learning causality from time and perturbation

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Abstract

The goal of systems biology is to generate models for predicting how a system will react under untested conditions or in response to genetic perturbations. This paper discusses experimental and analytical approaches to deriving causal relationships in gene regulatory networks.

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Krouk, G., Lingeman, J., Colon, A. M., Coruzzi, G., & Shasha, D. (2013). Gene regulatory networks in plants: Learning causality from time and perturbation. Genome Biology, 14(6). https://doi.org/10.1186/gb-2013-14-6-123

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