Postoperative changes in aortocoronary saphenous vein grafts revisited. Angiographic studies at two weeks and at one year in two series of consecutive patients

Abstract

Comparison of aortocoronary saphenous vein graft status at two weeks and at one year was made in two series of patients. The early postoperative evaluation includes 122 patients of the first 138 operated in the authors' institution (182 grafts) and 83 subjects from a second series of 100 patients operated after modifications of surgical techniques (184 grafts). The one year follow up study was obtained in 105 patients of the first series (154 grafts) and in 67 of the second (152 grafts). The patency rate at two weeks was not significantly different between the two groups: 86.3% vs. 91.8%. A marked decrease of stenoses noted early at anastomotic sites was observed: 15% to 5.5% (P<0.025). The patency rate at one year improved from 67% to 85.5% (P<0.0005). Grafts having flows at operation of at least 50 ml/min had patency rates of 90% in both series. The patency in grafts with initial flows below 50 ml/min increased from 28% to 73% (P<0.0005). The incidence of late localized graft stenoses ≥40% decreased from 16.5% (P<0.025), and diffuse narrowing ≥40% was found in only 12% of the patent grafts at one year in the second series as compared to 31% in the first (P<0.001). These improved results do not appear to have been influenced by selection favoring better distal run off in grafted arteries nor by the introduction of sequential grafts to multiple coronary arteries in the second group. Modified surgical techniques may explain rhe improved results.