Sarcomas of bone

Abstract

Sarcomas of bone are a rare and diverse set of tumors that, although related in their primary location (bone), vary in their etiology, behavior, and treatment. In 2011, approximately 2,890 new cases of bone and joint cancers were diagnosed in the USA. Osteosarcoma, chondrosarcoma, and Ewing sarcoma are the most common primary tumors of bone, representing 30 %, 15 %, and 6 %, respectively, of all bone sarcomas. The remainder of bone sarcomas is made up of malignant fibrous histiocytoma, chordoma, adamantinoma, hemangioendothelioma, hemangiopericytoma, and low-grade fibrosarcoma of the bone.