Immune Neuropathies

Abstract

Immune-mediated neuropathies are a heterogeneous group of disorders affecting the peripheral nerves. The first immune-mediated neuropathy was reported in France during the First World War in 1916 when Guillain, Barré, and Strohl described two patients with acute onset weakness that was progressive and predominantly motor, both of which recovered spontaneously. Though similar cases were previously described in 1859 by Landry [1], Guillain and colleagues were the first to demonstrate the presence of areflexia and albuminocytological dissociation in the cerebrospinal fluid (CSF). The disease was subsequently named Guillain-Barré syndrome (GBS).