Experience in the treatment of meningitis associated with health care in pediatric patients

Abstract

Objective: The objective of the study was to describe our clinical experience in meningitis associated with health care (MAHC). Methods: A retrospective study included pediatric patients, with MAHC, from 2010 to 2017 Parametric variables were evaluated by media, standard deviation, media and interquartile range. Non-parametric variables were described by reasons and proportions, Chi-square IC 95%. Significant variables (p < 0.005) were evaluated by bivariate logistic regression model to identify related risks for adverse evolution. We obtained the approval of the research ethics committee of our hospital for publication of this data. Results: A total of 114 cases of MAHC in children were analyzed. There were Gram-negative bacilli (62.6%) and ESBL producers (42.4%). Mortality was higher amongst cases exposed to more than three antibiotics OR = 5.50 (IC 95%, LI 0.996, LS 30.36) sig 0.050 mortality correlation 0.847 Conclusions: Gram-negative bacteria are frequent in MAHC, mortality was correlated to exposition more than three antibiotics.