Matrix Metalloproteinases, Tissue Inhibitors of Metalloproteinase and Matrix Turnover and the Fate of Hepatic Stellate Cells

  • Jamil A
  • Iredale J
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Abstract

Liver injury is associated with activation of hepatic stellate cells (HSC) to a myofibroblast-like phenotype. In cirrhotic liver injury, activated HSCs are the major source of fibrillar collagens, an excess of which characterise fibrotic matrix. HSCs also have the...

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Jamil, A. M., & Iredale, J. P. (2007). Matrix Metalloproteinases, Tissue Inhibitors of Metalloproteinase and Matrix Turnover and the Fate of Hepatic Stellate Cells. In Tissue Repair, Contraction and the Myofibroblast (pp. 102–109). Springer US. https://doi.org/10.1007/0-387-33650-8_11

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