Structure terminale des chromosomes: Le «capuchon télomérique»

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Abstract

The telomeres are the nucleoproteic structures present at the ends of eukaryotic chromosomes. One can compare them to the protective ends of a shoelace; when the ends get eroded, the shoelace disintegrates and we dispose of it. The same thus applies to the chromosomes; when telomeres reach a critical threshold for function, the genome becomes unstable and the cell senesces. Therefore, telomeres, and particularly their terminal DNA structures, are critical for the integrity of the genome.

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LeBel, C., & Wellinger, R. J. (2004). Structure terminale des chromosomes: Le «capuchon télomérique». Medecine/Sciences. Elsevier Masson SAS. https://doi.org/10.1051/medsci/2004202207

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