The telomeres are the nucleoproteic structures present at the ends of eukaryotic chromosomes. One can compare them to the protective ends of a shoelace; when the ends get eroded, the shoelace disintegrates and we dispose of it. The same thus applies to the chromosomes; when telomeres reach a critical threshold for function, the genome becomes unstable and the cell senesces. Therefore, telomeres, and particularly their terminal DNA structures, are critical for the integrity of the genome.
CITATION STYLE
LeBel, C., & Wellinger, R. J. (2004). Structure terminale des chromosomes: Le «capuchon télomérique». Medecine/Sciences. Elsevier Masson SAS. https://doi.org/10.1051/medsci/2004202207
Mendeley helps you to discover research relevant for your work.