Three cases of schizophrenia treated with L-dopa

Abstract

in three cases of schizophrenia, ill for three - six years with no sign of remission under various psychopharmacotherapies, l-dopa was used with the major tranquilizers which had previously been used. subsequently, remarkable recovery was noted. the tentative dosage of l-dopa in this research was 400-1200 mg per day. hallucination and thought disorder had disappeared as well as apathy and lack of spontaneity. in one case, upon the suspension of l-dopa, the patient's symptoms exacerbated. continuous administration of l-dopa is necessary for the improvement of the symptoms. © 1971, Kurume University School of Medicine. All rights reserved.