Atividade antibacteriana de plantas úteis e constituintes químicos da raiz de Copernicia prunifera

Abstract

Ethanol extracts of Qualea grandifl ora and Copernicia prunifera and hexane extract of Dipteryx lacunifera were evaluated by diffusion in agar and minimum inhibitory concentration (MIC) against Gram-positive and Gram-negative bacteria including multiresistant drug strains. The extract of Q. grandifl ora presented moderate activity for Staphylococcus epidermidis (MIC = 500 ?g/mL) and weak activity against other Gram-positive strains and inactive for Gram-negative species. The results obtained for S. epidermidis despite being moderate are important because this pathogen is often recovered from bacteremia and sepsis from infections of implanted devices. ?-Tocopherol and the mixture of sitosterol and stigmasterol were isolated from the ethanol extract of the roots of C. prunifera. The structures of these compounds were identifi ed by NMR spectroscopy and comparison with literature data.