To delineate the mechanisms contributing to the high level of antimicrobial resistance often demonstrated by Xanthomonas maltophilia, plasmid DNA was isolated from 5 clinical isolates and analyzed. Purified plasmid DNA from a single isolate contained a 6.5 kb plasmid (pXM222) and a 5.6 kb plasmid, (pTHB). Transformation of pTHB into E. coli HB101 resulted in the expression of resistance to all penicillins tested and cefazolin.
CITATION STYLE
Kelly, M. D., & Mortensen, J. E. (1996). A low-copy number plasmid mediating β-lactamase production by Xanthomonas maltophilia. In Advances in Experimental Medicine and Biology (Vol. 390, pp. 71–80). https://doi.org/10.1007/978-1-4757-9203-4_6
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