Understanding the Mechanisms of Local Pulmonary Drug Absorption and Metabolism: An in Vitro Model of the Airway Epithelium

Abstract

A review presents a brief summary of studies done with one of the most important cell cultures, the human submucosal cell line Calu-3. In vitro test systems like the Calu-3 cell line are valuable tools to understand absorption and metab. of drugs applied locally to the lung. [on SciFinder (R)]