Injection of autologous fat obtained by liposuction has been reported as an augmentation technique for vocal fold paralysis. Unfortunately, it is not known whether this technique is associated with long-term graft survival. The purpose of this study, using a canine model, was to determine the volume of viable injected fat grafts when the tissue was harvested and processed by two different methods: 1. by liposuction alone, and 2. by “purification,” i.e., excision of adipose tissue, followed by tissue homogenization and centrifugation in a buffering solution. The results of this study confirm that injected fat grafts survive long-term; however, the average volumetric “take” was only about 20%. Surprisingly, significantly more liposuctioned fat survived than grafts prepared by the purification method (P
CITATION STYLE
Mikus, J. L., Koufman, J. A., & Kilpatrick, S. E. (1995). Fate of liposuctioned and purified autologous fat injections in the canine vocal fold. Laryngoscope, 105(1), 17–22. https://doi.org/10.1288/00005537-199501000-00007
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