Endodontic management of open apex using MTA and platelet - rich fibrin membrane barrier: A newer matrix concept

13Citations
Citations of this article
50Readers
Mendeley users who have this article in their library.

Abstract

Objectives: Endodontic management of open apex using MTA and platelet - rich fibrin membrane as an apical matrix barrier. Study design: An immature tooth with pulpal necrosis and periapical pathology imposes a great difficulty to the endodontist. Endodontic treatment options for such teeth consist of conventional apexification procedure with and without apical barriers. This article demonstrates the use of an apical matrix barrier in form of a platelet rich fibrin membrane for stabilization of MTA in root end apexification procedure. PRF is an autologous fibrin matrix containing a large quantity of platelet and leukocyte cytokines, which enhance healing by release of growth factors. These case reports present apexification and successful healing with combined use of MTA and PRF membrane as an apical barrier Results: PRF membrane can serve as an efficient apical matrix for condensation of MTA. Combination of PRF membrane and MTA is an effective method for management of difficult cases of open apex. PRF is a strong fibrin membrane enriched with platelet and growth factors that accelerate periapical healing. © Medicina Oral S. L.

References Powered by Scopus

Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part I: Technological concepts and evolution

1292Citations
N/AReaders
Get full text

Platelet-rich fibrin increases proliferation and differentiation of human dental pulp cells

143Citations
N/AReaders
Get full text

The use of MTA in teeth with necrotic pulps and open apices

135Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Regenerative Endodontic Treatment or Mineral Trioxide Aggregate Apical Plug in Teeth with Necrotic Pulps and Open Apices: A Systematic Review and Meta-analysis

164Citations
N/AReaders
Get full text

Efficacy of Autologous Platelet Concentrates in Regenerative Endodontic Treatment: A Systematic Review of Human Studies

43Citations
N/AReaders
Get full text

Combination of Mineral Trioxide Aggregate and Platelet-rich Fibrin Promotes the Odontoblastic Differentiation and Mineralization of Human Dental Pulp Cells via BMP/Smad Signaling Pathway

41Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Khetarpal, A., Chaudhry, S., Talwar, S., & Verma, M. (2013). Endodontic management of open apex using MTA and platelet - rich fibrin membrane barrier: A newer matrix concept. Journal of Clinical and Experimental Dentistry, 5(5), 291–294. https://doi.org/10.4317/jced.51178

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 23

72%

Researcher 6

19%

Lecturer / Post doc 3

9%

Readers' Discipline

Tooltip

Medicine and Dentistry 38

93%

Agricultural and Biological Sciences 1

2%

Physics and Astronomy 1

2%

Immunology and Microbiology 1

2%

Save time finding and organizing research with Mendeley

Sign up for free