We developed an infant circulation model which incorporates an accurate myocardial cell model including a beta adrenergic system. The beta adrenergic system is essential for the response reproduction of the baroreflex control system. The proposed model was constructed by modifying the parameters of a human adult circulation model with the aid of a guinea pig myocardial cell model, whose baseline heart rate is close to that of an infant. The presented model is in good agreement with results obtained in physiological experiments. © Springer-Verlag Berlin Heidelberg 2007.
CITATION STYLE
Nobuaki, Y., Amano, A., Shimayoshi, T., Jianyin, L., Shim, E. B., & Matsuda, T. (2007). A model for simulation of infant cardiovascular response to orthostatic stress. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 4466 LNCS, pp. 190–199). Springer Verlag. https://doi.org/10.1007/978-3-540-72907-5_20
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