Incidence of Fusion Across Total Disc Replacement with Heterotopic Ossification: Are Ball and Socket Disk Replacements Fusing with and Without Radiographic Evidence

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Abstract

Study Design:This is a level III retrospective study.Objective:The authors aim to review the outcomes and complications of ball and socket total disk replacements (TDRs).Summary of Background Data:TDR is a motion-preserving technique that closely reproduces physiologic kinematics of the cervical spine. However, heterotopic ossification and spontaneous fusion after implantation of the total cervical disk have been reported in several studies to decrease the range of motion postulated by in vitro and in vivo biomechanical studies.Methods:The medical records of 117 consecutive patients undergoing cervical TDR over a 5-year period with Mobi-C, Prodisc-C, Prestige LP, and Secure-C implants were followed. Outcomes assessed included Visual Analogue Scale neck and arm and Neck Disability Index scores. The radiographic assessment looked at heterotopic ossification leading to fusion and complication rates.Results:Of the 117 patients that underwent TDR, 56% were male with the group's mean age being 46.2±10.3 years and body mass index of 18.9±13.6 kg/m2. The longest follow-up was 5 years with Prodisc-C group, with overall fusion noted in 16% of patients. One patient was also noted to have fusion which was not seen radiographically but noted intraoperatively for adjacent segment disease. There has been no demonstrable radiographic fusion seen in the Prestige LP group, however, the follow-up has only been 12-24 months for this group.Conclusion:In this study, we have demonstrated radiographic fusion anterior to the ball and socket TDR as well as the uncovertebral joint. We postulate that with the use of a mobile core disk there is an increased potential for fusion leading to a nonfunctional disk replacement.

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Chin, K. R., Pencle, F. J. R., Mustafa, L. S., Mustafa, M. S., Quijada, K. A., & Seale, J. A. (2019). Incidence of Fusion Across Total Disc Replacement with Heterotopic Ossification: Are Ball and Socket Disk Replacements Fusing with and Without Radiographic Evidence. Clinical Spine Surgery, 32(10), E469–E473. https://doi.org/10.1097/BSD.0000000000000866

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