Combining PEDOT:PSS Polymer Coating with Metallic 3D Nanowires Electrodes to Achieve High Electrochemical Performances for Neuronal Interfacing Applications

15Citations
Citations of this article
29Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

This study presents a novel approach to improve the performance of microelectrode arrays (MEAs) used for electrophysiological studies of neuronal networks. The integration of 3D nanowires (NWs) with MEAs increases the surface-to-volume ratio, which enables subcellular interactions and high-resolution neuronal signal recording. However, these devices suffer from high initial interface impedance and limited charge transfer capacity due to their small effective area. To overcome these limitations, the integration of conductive polymer coatings, poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) is investigated as a mean of improving the charge transfer capacity and biocompatibility of MEAs. The study combines platinum silicide-based metallic 3D nanowires electrodes with electrodeposited PEDOT:PSS coatings to deposit ultra-thin (<50 nm) layers of conductive polymer onto metallic electrodes with very high selectivity. The polymer-coated electrodes were fully characterized electrochemically and morphologically to establish a direct relationship between synthesis conditions, morphology, and conductive features. Results show that PEDOT-coated electrodes exhibit thickness-dependent improved stimulation and recording performances, offering new perspectives for neuronal interfacing with optimal cell engulfment to enable the study of neuronal activity with acute spatial and signal resolution at the sub-cellular level.

References Powered by Scopus

Neural stimulation and recording electrodes

1802Citations
N/AReaders
Get full text

Electrical stimulation of excitable tissue: Design of efficacious and safe protocols

1651Citations
N/AReaders
Get full text

Response of brain tissue to chronically implanted neural electrodes

1548Citations
N/AReaders
Get full text

Cited by Powered by Scopus

3D Printed Implantable Hydrogel Bioelectronics for Electrophysiological Monitoring and Electrical Modulation

51Citations
N/AReaders
Get full text

Sub-1-Volt Electrically Programmable Optical Modulator Based on Active Tamm Plasmon

10Citations
N/AReaders
Get full text

3D printing of highly conductive and strongly adhesive PEDOT:PSS hydrogel-based bioelectronic interface for accurate electromyography monitoring

9Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Muguet, I., Maziz, A., Mathieu, F., Mazenq, L., & Larrieu, G. (2023). Combining PEDOT:PSS Polymer Coating with Metallic 3D Nanowires Electrodes to Achieve High Electrochemical Performances for Neuronal Interfacing Applications. Advanced Materials, 35(39). https://doi.org/10.1002/adma.202302472

Readers over time

‘23‘24‘250481216

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 11

85%

Researcher 2

15%

Readers' Discipline

Tooltip

Engineering 4

36%

Materials Science 3

27%

Chemistry 2

18%

Physics and Astronomy 2

18%

Save time finding and organizing research with Mendeley

Sign up for free
0