Synthesis and biological evaluation of some quinazoline heterocyclic derivatives

Abstract

Owing to the significant biological activities, quinazoline derivatives have drawn more and more attention in the synthesis and bioactivities research. This chapter summarizes the recent advances in the investigations of synthesis and biological activities of quinazoline derivatives. According to the main method the authors adopted in their research design, those synthetic methods include microwave-assisted reaction, ultrasound-promoted reaction, metal-mediated reaction, water reaction, and phase-transfer catalysis reaction. The biological activities of the synthesized quinazoline derivatives are also discussed.