Biological scaffolds composed of extracellular matrix (ECM) are typically derived by processes that involve decellularization of tissues or organs. Here we describe a simple and robust methodology for the preparation of decellularized testicular matrix (DTM) scaffolds with minimal damage to the native three-dimensional structure and tissue-specific ECM components. Such DTM scaffolds can help to gain a better insight into the molecular composition and function of testicular ECM and to develop new tissue engineering approaches to treat various types of male fertility disorders.
CITATION STYLE
Baert, Y., & Goossens, E. (2018). Preparation of scaffolds from decellularized testicular matrix. In Methods in Molecular Biology (Vol. 1577, pp. 121–127). Humana Press Inc. https://doi.org/10.1007/7651_2017_29
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