Assessment of the Tumor Redox Status in Head and Neck Cancer by 62Cu-ATSM PET

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Abstract

Purpose Tumor redox is an important factor for cancer progression, resistance to treatments, and a poor prognosis. The aim of the present study was to define tumor redox (over-reduction) using 62Cu-diacetyl-bis(N4 -methylthiosemicarbazone) (62 Cu-ATSM) PET and compare its prognostic potential in head and neck cancer (HNC) with that of 2-deoxy-2-[18 F]fluoro-Dglucose (18 F-FDG).

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Tsujikawa, T., Asahi, S., Oh, M., Sato, Y., Narita, N., Makino, A., … Okazawa, H. (2016). Assessment of the Tumor Redox Status in Head and Neck Cancer by 62Cu-ATSM PET. PLoS ONE, 11(5). https://doi.org/10.1371/journal.pone.0155635

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