Other Multifactorial Disorders for Which Genetic/Genomic Testing Is Providing Insights

Abstract

This chapter describes the progress that has been made in personalizing medicine in several fields other than cancer and cardiovascular disease. A brief review is given of the gene variants that help predict, diagnose and treat age-related macular degeneration, type 2 diabetes mellitus, psychiatric disorders, substance abuse, Alzheimer disease and age-related cognitive decline, asthma and other respiratory disorders. The chapter discusses the clinically useful tests that have already been developed, several promising early discoveries that must now be reevaluated, and a number of basic research discoveries that will provide the basis for developing clinically useful tests in the near future.