Detection of the Asian II genotype of dengue virus serotype 2 in humans and mosquitoes in Brazil

Abstract

Introduction: DENV-2 is the cause of most dengue epidemics worldwide and is associated with severe cases. Methods: We investigated arboviruses in 164 serum samples collected from patients presenting with clinical symptoms of dengue fever and 152 mosquito pools. Results: We detected the Asian II genotype of DENV-2 in humans and mosquitoes. Our results confirmed the circulation of the Asian II genotype in Brazil, in addition to the prevalent Asian/American genotype. Conclusions: The detection of Asian II genotype of DENV-2 in mosquito pools collected in a forest park may be related to a spillback event of human dengue virus.