Cardiovascular risk in Turner syndrome

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Abstract

Turner syndrome is a relatively common genetic disorder of female development, characterized by partial or complete absence of an X chromosome, with a variable clinical presentation. Congenital or acquired cardiovascular disease is highly prevalent and a major cause of early death in this syndrome. The most feared complication is aortic dissection, which can occur at a very young age and requires careful assessment of its risk factors. A systematic literature search identified sixty relevant publications. These were reviewed with regard to the increased risk of cardiovascular disease in women with Turner syndrome, especially in pregnancy. The most common congenital cardiovascular defects are presented and illustrated with appropriate iconography. The current recommendations regarding the screening and monitoring of cardiovascular disease in these patients are discussed.

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Donato, B., & Ferreira, M. J. (2018, July 1). Cardiovascular risk in Turner syndrome. Revista Portuguesa de Cardiologia. Sociedade Portuguesa de Cardiologia. https://doi.org/10.1016/j.repc.2017.08.008

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