Diabetic retinopathy: Study of the action of 0-betahydroxyethyl-rutosides (HR) by retinal fluoresceinography

Abstract

The action of 0-beta-hydroxyethyl-rutosides (HR) on diabetic retinopathy has been evaluated on 20 diabetic patients by means of fluoresceinography. - The natural evolution and the evolution after treatment with HR (2400 mg orally per day) have been compared during periods of observation of 2 months. The administration of the medication and placebo, as well as the interpretation of the results, has been carried out on a double-blind basis. - The administration of HR causes a statistically significant reduction of the retinal vascular permeability to fluorescein. © 1970 Springer-Verlag.