Salinomycin, a new polyether antibiotic

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Abstract

Salinomycin is a new polyether antibiotic produced by a strain of Streptomyces albus (ATCC 21838). The antibiotic is purified by solvent extraction followed by chromatography on alumina or silica gel. It is a weakly acidic compound and has the molecular formula C42H70O11. Salinomycin exhibits activity against gram-positive bacteria including mycobacteria and some filamentous fungi. and is effective in the treatment of coccidial infection of poultry. © 1974, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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Miyazaki, Y., Shibuya, M., Sugawara, H., Kawaguchi, O., Hirose, C., Nagatsu, J., & Esumi, S. (1974). Salinomycin, a new polyether antibiotic. The Journal of Antibiotics, 27(11), 814–821. https://doi.org/10.7164/antibiotics.27.814

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