Characterization of iturin a in antibiotics from various strains of bacillus subtilis

Abstract

Iturin A, an antifungal lipopeptide characterized by the presence of homologous liposoluble β-aminoacids was found to be the active component to bacillomycin B, bacillomycin R and eumycin. Iturin A was identified by thin-layer chromatography, aminoacid analysis and by characterization of liposoluble aminoacids and peptides. Another two preparations: the antibiotic of RAUBITSCHEK and the bacillomycin of LANDY et al. Contain components of the same structural type but they are different from iturin A. © 1976, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.