Neurologic signs and symptoms have been recognized in the setting of Sjögren’s syndrome (SS) since the syndrome was first described by Sjögren in 1935 [1]. In particular, peripheral nervous system involvement in primary SS (pSS) has been well characterized and is believed to affect approximately 10–20% of SS patients [2]. The frequency of central nervous system (CNS) involvement is less clear, however, as controversy exists regarding the frequency and type of CNS manifestations in pSS.
CITATION STYLE
Pillemer, S. R., Mendelsohn, A. B., & Morgen, K. E. (2012). Central nervous system involvement. In Sjogren’s Syndrome: Diagnosis and Therapeutics (pp. 281–291). Springer-Verlag London Ltd. https://doi.org/10.1007/978-0-85729-947-5_20
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