Mutagens alter DNA. As the DNA of all organisms has the same double helical structure and the same four nucleotides, any organism may be used as an indicator system for mutagens. Bacteria have numerous advantages for the detection of mutagens, and we discuss these and describe various methods and strains. We also discuss the validity of the bacterial tests and their pertinence to human mutagenesis and carcinogenesis.
CITATION STYLE
Ames, B. N. (1971). The Detection of Chemical Mutagens with Enteric Bacteria. In Chemical Mutagens (pp. 267–282). Springer US. https://doi.org/10.1007/978-1-4615-8966-2_9
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