Abstract
HIV-1 reverse transcriptase (RT) is responsible for conversion of the viral single-stranded (+)RNA into double-stranded DNA. The enzyme is multifunctional and possesses two distinct activities: (i) a DNA polymerase activity that can use either RNA or DNA as a template and (ii) a ribonuclease H (RNase H) activity that degrades the RNA strand in RNA/DNA duplexes.
Cite
CITATION STYLE
APA
Tachedjian, G., & Sluis-Cremer, N. (2013). Role of RNase H activity in NRTI/NNRTI drug resistance. In Human Immunodeficiency Virus Reverse Transcriptase: A Bench-to-Bedside Success (pp. 281–303). Springer New York. https://doi.org/10.1007/978-1-4614-7291-9_13
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Already have an account? Sign in
Sign up for free